Prof. Chang is a professor at the School of Medical Informatics, Chung Shan Medical University, and the Department of Information Management, Ming Chuan University. He also serves as the president of the Society for Asia Medical Decision Science (SAMDS) and the Medical Decision Science Association of Taiwan. He joined the International Advisory Board of Karadeniz Technical University, Ming Chuan University, Isparta University of Applied Sciences, Mongolian National University of Medical Sciences, Mongolian National University of Medical Sciences and Süleyman Demirel University to support their internationalization efforts. Additionally, he has played a key role in facilitating the signing of Memoranda of Understanding (MOUs) between these universities and various research institutions around the world, fostering international collaboration in education and research programs.

His research contributions are focuses on clinical studies of specific diseases, including predicting cancer recurrence and Second Primary Cancer, diagnosing glaucoma and early chronic kidney disease, and analyzing posttraumatic growth and health behavior in clinical psychology. For practice issue, his team apply several innovative information technologies and collaborate across disciplines and countries around the world. He has published more than 150 peer-reviewed articles in reputed international journals and conferences. Prof. Chang have co-founded three international conferences, two AI forums, and the Medical Decision Science Association of Taiwan with his team members. There are the International Conference on Medical and Health Informatics (ICMHI) in 2017 [1], the International Conference on Healthcare Service Management (ICHSM) in 2018 [2], the Health Big Data, Analytics and Artificial Intelligence Forum (HBAAI) in 2017 [3], the Joint Executive Board on Medical Informatics Taiwan (JEBMI) in 2018 [4] and the Medical Decision Science Association of Taiwan (MDSAT) in 2022 [5], the International Symposium on Medical Decision Science (ISMDS) in 2023 [6], the Medical Decision Science Association of Mongolia (MDSAM) [7] and Society for Asia Medical Decision Science (SAMDS) [8]

He is the founding Editor-in-Chief of the Decision Science in Medicine. He also an editor for some interdisciplinary journals, including those in the fields of medicine, computer science, and management science, include Intl Journal of Medical Sciences, Open Medicine, Therapeutics & Clinical Risk Management, Diagnostic, Intl Journal of Environmental Research and Public Health, Frontiers in Genetics, Journal of Universal Computer Science, Intl Journal of Computers and Applications, Journal of Quality, Journal of Computing Science and Engineering, Intl Journal of Business and Systems Research, ACM, Intl Journal of Management, Economics and Social Sciences and Journal of Electronic Science and Technology etc.